FYI: Be careful of what you download...

[s2driveruk]

downloaded firefox and new clean versions of MBAM and Combofix, deselected IE8 and then it locked some registry keys during a scan, combofix noted the issue and rebooted to disinfect. On trying to complete the disinfection, it then decided to revoke access to firefox and then basically disabled use of the PC, on rebooting, it suggested it was installing updates then locked it to a cycle of saying installing updates then rebooting itself.

Am totally gobsmacked at the virulent nature of this feckin infection. Anyway, waiting to buy a copy of Win 7 then doing a clean install.

[rj scotty]

Format and rebuild system annually, speeds things up massively to boot

[macspring]

Get a mac, problem solved

(sorry if that was not what you wanted to here mate)

+ 1.

[irishs2]

Having windows running and trying to repair it at the same time can be problematic.
Sometimes you can use hijackthis to identify the executable(s) and then boot with a recovery cd, either a ubuntu disk or xp recovery prompt and manually delete it, then boot normally and deal with the aftermath.
However there might be an easier way, If you download this cd image http://trinityhome.org and burn to cd/dvd or usb stick, and use one of the built in virus scanners to fix your pc. I would also recommend getting a avast home key emailed to yourself from www.avast.com, beforehand and use the key with avast on the cd. http://www.avast.com/en-eu/registrat...-antivirus.php Trinity is pretty cool, as it gives access to network, to download updates also.

Trinity can do so much more than just virus scan, it allows cloning, mbr repair, password recovery, network sharing hd, the list goes on.